Home   |   Career Center   |   Contact Us   |   Sign In
Number 12-01: Ruptured Left Ventricular Aneurysm
Share |

Number 12-01: Ruptured Left Ventricular Aneurysm

Case from: Elisabetta Chiodi1, Donato Mele2, Andrea Fiorencis3
Institute: Departments of Radiology1 and Cardiology2, S.Anna Hospital Ferrara, University of Ferrara3 

Clinical history: 68 year old female, smoker, with a history of hyperlipidemia, and type 2 diabetes mellitus. In 2007 she suffered from a myocardial infarction with incomplete revascularization due to ineffective primary angioplasty. In 2009 an echocardiogram documented a left ventricular apical aneurysm and systolic dysfunction (25% ejection fraction). The patient refused an ICD at that time. In February 2010 she reconsidered the ICD as she represented with severe dyspnea.

Her presenting ECG demonstrated a sinus tachycardia of 120 bpm and a wide QRS consistent was a left bundle branch block.

An echocardiogram was performed (Movie 1) which demonstrated a severely dilated left ventricle with diffuse contractile dysfunction, 15% ejection fraction, and an unclear geometric distortion of the aneurysmal apex (Image 1).

 


                                                               

Movie 1:  Echocardiogram, apical four chamber                          Image 1: Echocardiogram, apical short axis

 

A noncontrasted gated cardiac CT was performed to further define the apical abnormality (Images 2 & 3).  The CT demonstrated a large disruption of the left ventricular apex with evidence of calcification near the collar of the defect.  There was also marked aortic calcification and bilateral pleural effusions.

 

                                                    

Image 2:  Chest CT demonstrating a contained                               Image 3: Chest CT demonstrating the LV
rupture of the LV apex with associated calcifcations                   apical defect with a wide collar and calcification            

                                                                                                              

 A Cardiac MRI (GE Twinspeed 1.5 T) was performed to further identify the possibility of concommitant LV aneurysm and pseudoaneurysm. Steady state free precession CINE MRI demonstrated severe left ventricular dysfunction, left ventricular apical remodeling with a 22 mm collar, and thrombotic stratification (Movie 2).

 


 

Movie 2: Cardiac MRI, short axis CINE stack

 

Delayed enhancement images demonstrated scar of the apex.  There was evidence of rupture of the aneurysmal wall with containment by a thin layer of parietal pericardium.

 

 

Figure 4: Delayed enhancement, pseudoaneurysm

 

Figure 5: Delayed enhancement, thrombus within
              the aneurysmal sac

 

Follow up: The patient underwent coronary angiography which revealed triple vessel disease involving the left anterior descending artery (occluded after a highly stenotic 1st diagonal branch), left circumflex coronary artery (90% stenosis), and right coronary (90% stenosis). Surgery was performed with successful coronary revascularization and pseudoaneurysm repair.

Perspective: Aneurysms typically occur due to myocardial infarction and scar. True aneurysms are bulges of myocardial tissue in areas of necrotic myocardium without disruption of the visceral pericardium. Pseudoaneurysms occur when a myocardial rupture occurs and is contained by parietal pericardium and fibrous tissue. Despite this containment, pseudoaneurysms have a high risk of rupture. Clinical presentation includes congestive heart failure (36%), chest pain (30%) and dyspnea (25%), while the incidence of sudden death at the onset is 3%.

Echocardiography is a valuable non-invasive tool for diagnosing aneurysms. However, in cases of inadequate image quality CMR is needed for final diagnosis.  The advantage of CMR is includes a high resolution evaluation of the myocardium, pericardium, and thrombi. Visualization of epicardial fat layer disruption at the site of the pseudoaneurysm is also possible. Additionally, this technique is highly accurate in determining the size and location of this abnormality for surgical planning.

The originality of this case is the simultaneous presence of both lesions, the true and pseudo-aneurysm, recognized by CMR. There are qualities present for true aneurysm (wide collar, delayed enhancement within the sac, chronicity of defect) and pseudoaneurysm (disruption of myocardium, thrombus within the pericardial space, involvement of the parietal pericardium).  Because early diagnosis is essential to determine the appropriate lesion treatment, CMR has played a decisive role in this case.

 

References:
1)Brown SL, Gropler RJ, Harris KM. Distinguishing left ventricular aneurysm from pseudoaneurysm. A review of the literature. Chest 1997;111: 1403-9.

2)Frances C, Romero A, Grady D. Left Ventricular Pseudoaneurysm. J Am Coll Cardiol 1998;32:557-61.

3)Contuzzi R, Gatto L, Patti G, Goffredo C, D'Ambrosio A, Covino E, Chello M, Di Sciascio G. Giant left ventricular pseudoaneurysm complicating an acute myocardial infarction in patient with previous cardiac surgery: a case report. J Cardiovasc Med (Hagerstown) 2009;10:81-84.

4) Konen E, Merchant N, Gutierrez C, Provost Y, Mickleborough L, Paul NS, Butany J. True versus false left ventricular aneurysm: differentiation with MR Imaging--initial experience. Radiology 2005;236:65-70.

5) Davutoglu V, Soydinc S, Sezen Y, Aksoy M. Unruptured giant left ventricular pseudoaneurysm complicating silent myocardial infarction in a diabetic young adult. Int J CV Imaging. 2005; 21: 231-234.

Submit your case here

COTW handling editor: Kevin Steel 

Have your say:  What do you think?  Latest posts on this topic from the forum


Re: Number 12-01: Ruptured LV Aneurysm
Dear All,as pointed by the patient was too dyspnoeic to lie in the cmr gantry and for this reason a non contrast ct was done before cmr. Thanksedit: patient first name removed. moderator. ...
On: 02/17/2012 By: chiodie Read more?

Re: Number 12-01: Ruptured LV Aneurysm
Good point Gurpreet. I am gonna contact the authors now. ...
On: 02/12/2012 By: chiarabd Read more?

Re: Number 12-01: Ruptured LV Aneurysm
I like the case! Though I have the same question as Dr Chiara regarding the need for ct. if I may try to answer this for the authors, maybe the patient was too dyspnoeic to lie in the cmr gantry,...
On: 02/11/2012 By: GULATIGURPREET Read more?

Re: Number 12-01: Ruptured LV Aneurysm
Nice case - like the combination of true and pseudoaneurysm. Good to see GE scanner use also. ...
On: 02/08/2012 By: moon Read more?

Number 12-01: Ruptured LV Aneurysm
An interesting case that it not uncommon to encounter in clinical practice. I guess my comment is around the need of performing a CT. CMR by itself would have been able to answer the question. ...
On: 02/07/2012 By: chiarabd Read more?

 

Membership Software Powered by YourMembership.com®  ::  Legal